● Xa kuthelekiswa ne-PRP, akukho zongezelelo zangaphandle ezisetyenziselwa ukulungiswa kwe-PRF, ekhusela umngcipheko wokulahlwa komzimba, ukusuleleka kwintsholongwane kunye nokungasebenzi kakuhle kwe-coagulation.Iteknoloji yokulungiselela yenziwe lula.Inyathelo elinye le-centrifugation, efuna kuphela i-centrifuged ngesantya esiphantsi emva kokuthatha igazi kwityhubhu ye-centrifuge.I-silicon element kwi-glass centrifuge tube ikhuthaza i-polymerization ye-physiological ye-activation platelet kunye ne-fibrin, ukulinganisa kwenkqubo ye-physiological coagulation iqalisiwe kwaye amahlule endalo aqokelelwa.
● Ngokombono we-ultrastructure, kufunyenwe ukuba ukuhambelana okuhlukeneyo kwesakhiwo se-fibrin reticular iyona nto iphambili yesakhiwo sezigaba ezibini, kwaye zihluke ngokucacileyo kubuninzi kunye nohlobo.Ubuninzi be-fibrin bunqunywe ngubuninzi be-fibrinogen yayo eluhlaza, kwaye uhlobo lwayo luxhomekeke kwisixa esipheleleyo se-thrombin kunye nesantya se-polymerization.Kwinkqubo yokulungiselela i-PRP yendabuko, i-polymerized fibrin ilahlwa ngokuthe ngqo ngenxa yokuchithwa kwayo kwi-PPP.Ngoko ke, xa i-thrombin yongezwa kwinyathelo lesithathu ukukhuthaza ukudibanisa, umxholo we-fibrinogen uncitshiswe kakhulu, ukuze ubuninzi besakhiwo sothungelwano lwe-polymerized fibrin lungaphantsi kakhulu kunolo lwegazi legazi, ngenxa yesiphumo se-Exogenous. Izongezo, ukugxilwa kwe-thrombin ephezulu kwenza isantya se-polymerization ye-fibrinogen siphakame kakhulu kuneso sokusabela komzimba.Inethiwekhi ye-fibrin eyenziwe yi-polymerization yeemolekyuli ezine ze-fibrinogen, eziqinileyo kunye nokungabikho kwe-elasticity, okungenakulungele ukuqokelela i-cytokines kunye nokukhuthaza ukufuduka kweeseli.Ngoko ke, ukuvuthwa kwenethiwekhi ye-PRF ye-fibrin ingcono kune-PRP, esondeleyo kwimeko ye-physiological state.
