"Isampuli ye-hemolysis ngowona mthombo wemposiso eqhelekileyo kwilabhoratri yeklinikhi kunye nesizathu esiyintloko sokulahlwa kwesampuli. Ingxelo yesiphumo esingalunganga ngenxa yesampula ye-hemolysis inokukhokelela ekuxilongeni kakubi kunye nokuphathwa kakubi, ukuzotywa kwegazi kwakhona kuya kwandisa intlungu yezigulane, ukwandisa umjikelo wokunika ingxelo, kwaye kubangele ilahleko yabantu, impahla kunye nezoqoqosho"
1) Indlela yokugweba i-hemolysis?
Ngokuqhelekileyo, isampuli emva kwe-centrifugation ijongwa ukugweba ukuba i-hemolytic, kodwa ngamanye amaxesha isampuli ibomvu ebomvu ngenxa ye-vibration yokungakhathali emva kwe-centrifugation, eya kuthathwa njenge-hemolysis ukuba ayijongwa ngononophelo.Ngoko ke, sinokufumanisa njani ukuba yi-hemolysis yokwenene?Indlela engcono kakhulu kukulinganisa umxholo we-hemoglobin kwi-serum, oko kukuthi, isalathisi se-hemolysis, ukwazi ukuba kukho i-hemolysis.
Uyichaza njani ukuba isampuli inovavanyo lweklinikhi olunxulumene ne-hemolysis?Okwangoku, indlela eqhelekileyo kukugweba ngokwesalathisi se-hemolysis (HI).Isalathisi se-Hemolysis ngokwenene lizinga le-hemoglobin yamahhala kwi-plasma.Abanye abaphandi bathelekisa izifundo ze-50 kwi-hemolysis kwaye bafumanisa ukuba i-20 isebenzise i-hemolysis index ukuchaza i-hemolysis, i-19 isebenzise ukuhlolwa okubonakalayo, kwaye enye i-11 ayizange ibonise indlela.
Umkhuba wokusebenzisa i-hemolysis ebonakalayo ukukhetha iisampulu zeklinikhi kuthathwa njengokungachanekanga ngenxa yokungabikho kwemigangatho yobungakanani benjongo kunye novakalelo lwezalathi ezahlukeneyo kwi-hemolysis.Kuphononongo kwi-cludia ngo-2018, abantu balandele ngononophelo iisampulu zegazi ezingama-495 kunye neziphumo zovavanyo kwigumbi likaxakeka.Kwafunyaniswa ukuba isigwebo esibonakalayo se-hemolysis singakhokelela kwiziphumo zovavanyo ezingafanelekanga ukuya kwi-31%, kubandakanywa ne-20.7% yamatyala apho i-hemolysis yayinempembelelo kwiziphumo kodwa yayingahoywa, kunye ne-10.3% yamatyala apho iziphumo zovavanyo zimisiwe kodwa kamva. ifunyenwe ingachatshazelwa yi-hemolysis.
2) Iimbangela ze-hemolysis
Iimbangela ze-hemolysis zinokwahlulwa zibe luvavanyo lweklinikhi olunxulumene ne-hemolysis kunye novavanyo olungelulo lwezonyango olunxulumene ne-hemolysis ngokwembono yokuba ingaba ziyahambelana nenkqubo yovavanyo lweklinikhi.Uvavanyo lweklinikhi olunxulumene ne-hemolysis lubhekiselele kwi-hemolysis ebangelwa ukugqabhuka kweeseli ezibomvu zegazi ngenxa yokusebenza ngokungafanelekanga kovavanyo lweklinikhi, eyona nto igxininise kwingxoxo yethu.Ukusebenza kweklinikhi kunye noncwadi olufanelekileyo luye lwabonisa ukuba ukuvela kwe-hemolysis kuhambelana ngqo nenkqubo yokuqokelela isampuli.Kwinkqubo yovavanyo lweklinikhi, i-hemolysis iya kubangelwa ukuba i-caliber yenaliti yokuqokelela igazi incinci kakhulu, isantya somzobo wegazi sikhawuleza kakhulu, ukukhethwa kwendawo yokuqokelela igazi ayifanelekanga, i-tourniquet isetyenziselwa ixesha elide, ukuqokelela kwegazi. isitya asigcwalanga, ukungcangcazela okugqithisileyo emva kokuqokelela igazi, ukungcangcazela okugqithisileyo ngexesha lothutho, njl. njl. Inokwahlulwa kwezi zilandelayo:
2.1 Ukuqokelelwa kwemizekelo
Ukulimala kokuqokelela igazi, njengokufakwa kwenaliti ngokuphindaphindiweyo kunye nokuqokelela igazi kwi-hematoma;Ukuqokelela igazi kwizixhobo zokufikelela kwi-vascular ezifana ne-venous indwelling, ityhubhu yokufakelwa kunye ne-catheter ye-venous ephakathi;Ukuqokelelwa kwegazi kwesirinji;I-anterior median cubital vein, i-cephalic vein kunye ne-basilic vein ayikhethwanga;Sebenzisa inaliti entle;Isibulali-ntsholongwane asomile;Sebenzisa i-tourniquet ngaphezu komzuzu omnye;Ukungaphumeleli ukuxuba ngexesha kunye nokuxuba ngobudlova;Umthamo wokuqokelela igazi awunelanga kwaye awufikeleli kwisikali sokulinganisa i-vacuum yesitya sokuqokelela igazi;Umgangatho wesitya sokuqokelela igazi le-vacuum kunye nokwahlula iglue kubi;Sebenzisa umthamo omkhulu wemithanjana yokuqokelela igazi, njl.
2.2 Umzekelo wezothutho
Ukungcangcazela okunobundlobongela ngexesha lokudluliselwa kwe-pneumatic;Ixesha elide lokuhamba;Ubushushu besithuthi sokudlulisa buphezulu kakhulu, ukungcangcazela okunobundlobongela, njl.
2.3 Ukusetyenzwa kwesampuli yeLabhoratri kunye ne-Hemolysis kwi-vivo
Ixesha elide lokugcinwa kweesampuli;Ubushushu bokugcinwa kweesampulu buphezulu kakhulu;Ayigxininisi ngexesha;Igazi lalingajingi ngokupheleleyo ngaphambi kokuba libe phakathi;Ubushushu be-centrifugal buphezulu kakhulu kwaye isantya sikhawuleza kakhulu;Re centrifugation, njl.
I-Autoimmune hemolytic, njengokungahambelani kweqela legazi kunye nokumpontshelwa igazi;Izifo ze-Genetic kunye ne-metabolic, ezifana ne-thalassemia kunye ne-hepatolenticular degeneration;Iziyobisi hemolytic reaction emva amayeza, ezifana acute hemolytic reaction ebangelwa inaliti emithanjeni ceftriaxone sodium;Usulelo oluqatha;Ukusasazwa kwe-intravascular coagulation;I-stent ye-cardiac, i-valve ye-artificial heart, i-extracorporeal membrane oxygenation, njl njl. Isampuli ye-hemolysis ebangelwa yi-hemolysis kwi-vivo ayiyi kukhatywa ilebhu, kwaye ugqirha uya kumakisha inkcazo kwifom yesicelo.
Ixesha lokuposa: Apr-07-2022